shining a light on how hormones are metabolized

Main points video

How are hormones metabolized?

Based on information taught in Karen Hurd's e-course on hormonal overproduction

  • a first thing to consider: once a hormone is created by the endocrine system — and once it has done its job — we have to metabolize it in order to get rid it

Role of the liver in metabolization of hormones

  • the liver is responsible for clearing hormones out of the bloodstream
  • the only exit the liver has to excrete these hormones, is through the gastro-intestinal (GI) tract 
  • hormonal waste will enter the GI tract to eventually be pooped out 
  • are you pooping on a daily basis? 
  • two main female sex hormones are estrogen & progesterone, and they are fat-soluble>> these hormones then turn into fat-soluble waste products 
  • the liver is responsible for clearing out all fat-soluble waste products

Recap: liver pulls fat-soluble hormones out of the bloodstream>> sends them down the GI tract to be eliminated via stool 

However… for these hormones to be able travel down the GI tract, they need to be put into a carrier: the digestive fluid bile

  • bile is responsible for getting rid of fat-soluble metabolic waste
  • the bile carrying the metabolic waste will first land into the small intestine
  • right before the small intestine turns into the large intestine, we have the ileum
  • part of the ileum is the ileocecal valve >> here, there is an absorption fatty substances

Recap: the bile is carrying the hormonal waste, which is made out of fat… and at the end of the ileum, we have an absorption of fat 

  • it is possible for us to reabsorb our own hormonal waste! 
  • up to 95% of our bile is recycled
  • this mechanism (for energy preservation) is called the enterohepatic recirculation 

If our hormones have the opportunity to re-enter our bloodstream...

  • they are able to cause chemical reactions to happen again 
  • and... our body doesn’t stop producing new hormones in the meantime
  • and... it is possible for the body to recycle hormones we’ve produced over time

… this explains how we can eventually end up with an over-expression of hormones 

Complete and Continue